CME Accreditation & Disclosure
ACCME-compliant faculty disclosures, accreditation statement, and course learning objectives.
Accreditation Statement
MetFix Medical Education is applying for accreditation as a provider of continuing medical education for physicians through the Accreditation Council for Continuing Medical Education (ACCME). Upon accreditation, this activity will be designated for AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Commercial Support & Independence
This CME activity has received no commercial support from pharmaceutical companies, medical device manufacturers, or other commercial interests. MetFix Medical Education retains full editorial control over all course content. No faculty member has been compensated by a commercial interest for participation in this activity.
Content referencing specific commercial products (CGM platforms, food tracking applications, clinical programs) is included solely on the basis of clinical evidence and educational utility. Inclusion does not constitute endorsement, and MetFix Medical Education receives no financial consideration from any referenced company.
Faculty Disclosures
In accordance with ACCME Standards for Integrity and Independence, all individuals in a position to control the content of this CME activity have disclosed all relevant financial relationships with ineligible companies within the past 24 months.
| Faculty | Role | Relevant Relationships | Resolution |
|---|---|---|---|
| MetFix Course Development Team | Course Director & Content Authors | None | Not applicable |
Off-Label / Investigational Use Disclosure
This course discusses the use of dietary interventions, specifically therapeutic carbohydrate restriction and ketogenic dietary protocols, for the management and reversal of type 2 diabetes mellitus, non-alcoholic fatty liver disease, and other metabolic conditions. While these interventions are supported by peer-reviewed clinical evidence, they may not be consistent with current FDA-approved indications for medications discussed in the context of deprescription protocols.
Physicians are advised to exercise independent clinical judgment and to consult current prescribing information before modifying or discontinuing medications in individual patients.
Learning Objectives by Module
Upon completion of this activity, participants will be able to achieve the following objectives, mapped to the HHS Medical Education Nutrition Competency (MENC) Framework domains.
- 1
Explain the Insulin/ROS Hypothesis as the unifying mechanistic framework for metabolic disease.
- 2
Describe the role of mitochondrial electron transport chain dysfunction in the pathogenesis of insulin resistance.
- 3
Differentiate between the metabolic effects of dietary carbohydrate, fat, and protein on fasting insulin and postprandial glucose.
- 4
Identify the cellular mechanisms by which chronic hyperinsulinemia drives reactive oxygen species production.
- 5
Apply the concept of metabolic flexibility to clinical dietary prescription.
- 1
Interpret fasting insulin, HOMA-IR, and TG:HDL ratio as early markers of insulin resistance preceding standard diagnostic criteria.
- 2
Construct a predictive metabolic panel and explain the clinical rationale for each component.
- 3
Distinguish between standard lipid panel limitations and advanced lipoprotein testing (LDL-P, sdLDL, ApoB) in metabolic risk assessment.
- 4
Identify patients with metabolic dysfunction who would be missed by standard HbA1c and fasting glucose screening.
- 5
Apply continuous glucose monitoring data to dietary counseling and metabolic assessment.
- 1
Describe the evidence base for dietary carbohydrate restriction in the reversal of type 2 diabetes mellitus.
- 2
Construct a disease-specific nutritional protocol for T2DM, NAFLD, hypertension, and dyslipidemia.
- 3
Explain the mechanism by which a well-formulated ketogenic diet reduces hepatic fat in NAFLD.
- 4
Identify the clinical criteria for initiating a deprescription protocol as metabolic markers improve.
- 5
Apply the Virta Health 5-year outcomes data to patient counseling on diabetes reversal.
- 1
Apply the four principles of the Harvard Program on Negotiation to dietary behavior change counseling.
- 2
Stage patients using the Transtheoretical Model and select the appropriate counseling intervention for each stage.
- 3
Demonstrate motivational interviewing techniques for patients in the precontemplation and contemplation stages.
- 4
Identify the limitations of standard RDN training relevant to low-carbohydrate dietary counseling.
- 5
Describe the MetFix physician-coach model and the division of clinical and behavioral responsibilities.
- 6
Recommend appropriate patient-facing tools (CGM platforms, food tracking apps, daily recipe resources) to reduce dietary transition barriers.
- 1
Trace the historical development of the Diet-Heart Hypothesis from Ancel Keys' Seven Countries Study to current policy.
- 2
Identify the methodological flaws in the foundational studies supporting the low-fat dietary guideline.
- 3
Describe the role of industry funding in shaping nutritional research and federal dietary policy.
- 4
Explain the significance of suppressed RCT data (Sydney Diet Heart Study, Minnesota Coronary Experiment) for current clinical practice.
- 5
Evaluate the 2026 HHS/USDA dietary guidelines overhaul in the context of the historical evidence base.
- 1
Describe the structural features of the US food system that promote metabolic disease at the population level.
- 2
Identify the policy mechanisms (agricultural subsidies, school nutrition standards, food labeling) that a physician-advocate can target.
- 3
Apply the principles of physician advocacy to institutional and policy-level dietary change.
- 4
Evaluate the evidence for food-as-medicine programs and their integration into clinical practice.
- 5
Construct a practice-level metabolic health initiative appropriate to the physician's clinical setting.
Assessment & Completion Requirements
Read all sections
All 18 sections across 6 modules must be marked complete.
Complete interactive labs
Each module includes one interactive clinical lab that must be completed.
Pass all knowledge checks
A minimum score of 70% is required on each module knowledge check. Unlimited retries are permitted after a 24-hour waiting period.
Complete the post-test
A 30-question cumulative post-test covering all 6 modules must be completed with a minimum score of 70% to unlock the certificate.
Complete the evaluation
A brief course evaluation must be submitted before the certificate is issued, in accordance with ACCME requirements.