MetFix Medical Nutrition - Faculty & Curriculum Committee Guide
The Science of Metabolic Medicine
A 40-Hour CME-Eligible Curriculum for Medical Students and Physicians
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HHS Competencies Addressed
Executive Summary
The MetFix Medical Nutrition curriculum is a structured, evidence-based 40-hour course designed to equip medical students and physicians with the clinical knowledge and practical skills to address the metabolic disease epidemic through dietary intervention. The curriculum satisfies the nutrition education requirement established by the U.S. Department of Health and Human Services and addresses all 71 HHS medical nutrition competencies across 10 domains.
The course is built on a deliberate pedagogical sequence: mechanism before measurement, measurement before intervention, intervention before counseling. Students first develop a mechanistic understanding of how diet drives metabolic disease at the mitochondrial level (Module 1), then learn to detect it before standard criteria are met (Module 2), then apply disease-specific dietary protocols (Module 3), and finally develop the communication skills to translate that knowledge into patient behavior change (Module 4). Modules 5 and 6 provide the historical and systems context that equips physicians to advocate for evidence-based nutrition policy.
The course is delivered as a self-paced web application with interactive visualizations, case-based quizzes, and a patient handout library. It is designed for integration as a standalone elective, a preclinical block, or a residency didactic series.
Regulatory & Accreditation Alignment
HHS Mandate
Satisfies the 40-hour minimum nutrition education requirement established by the U.S. Department of Health and Human Services under the MAHA Commission initiative.
LCME Standard 7.2
Addresses LCME standard requiring medical schools to include content on nutrition and its role in health promotion and disease prevention.
CME Eligibility
Structured for ACCME joint sponsorship. Post-test passage (≥70%) generates a certificate of completion. Suitable for AMA PRA Category 1 Credit™ designation.
ACGME Milestones
Addresses Patient Care and Medical Knowledge milestones related to preventive medicine, chronic disease management, and health promotion counseling.
MetFix Medical Nutrition - Faculty & Curriculum Committee Guide
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MetFix Medical Nutrition - Faculty Guide · Module Breakdown · Page 2 of 3
Course Structure - Module by Module
Why This Course Exists and How to Use It
Sections
1. A New Era for Nutrition in Medicine
2. How to Use This Course
3. The Clinical Opportunity
HHS Domains
Domain 5, Domain 6
Key Evidence Base
HHS 40-hour mandate; DiRECT trial (Lancet, 2018); Virta Health 5-year data
Module 1The Science of Metabolic Health
8 hrsThe Insulin/ROS Hypothesis and Mitochondrial Function
Sections
1. The Mitochondria: Beyond ATP Production
2. The Protons Hypothesis: ROS, the FADH₂:NADH Ratio, and Insulin Resistance
3. Macronutrients: Clinical Biochemistry
HHS Domains
Domain 1, Domain 2, Domain 3
Key Evidence Base
Dobromylskyj (Hyperlipid, 2013–2023); Speijer (BioEssays, 2011); Brand (Biochem J, 2016)
Module 2Clinical Assessment and Predictive Diagnostics
7 hrsIdentifying Metabolic Dysfunction Before Standard Criteria Are Met
Sections
1. The Limitations of Standard Metabolic Screening
2. The Predictive Diagnostic Panel
3. Physical Examination for Metabolic Disease
HHS Domains
Domain 5, Domain 6, Domain 7
Key Evidence Base
Kraft (1975); HOMA-IR validation (Matthews et al., 1985); TG:HDL ratio (McLaughlin et al., 2005)
Module 3Disease-Specific Nutritional Protocols
7 hrsDietary Reversal of Chronic Metabolic Disease
Sections
1. Type 2 Diabetes: Reversal, Not Management
2. Cardiovascular Disease: Beyond the Lipid Hypothesis
3. NAFLD, Metabolic Syndrome, and the Unified Treatment
HHS Domains
Domain 3, Domain 7, Domain 8
Key Evidence Base
DiRECT trial (Lean et al., 2018); Virta Health (Hallberg et al., 2018); PREDIMED (Estruch et al., 2018)
Module 4The Art of Patient Counseling
6 hrsHarvard Program on Negotiation Applied to Behavior Change
Sections
1. Why Dietary Behavior Change Fails: The Psychology of Resistance
2. The Harvard PON Framework for Patient Counseling
3. Working with Allied Health Professionals and MetFix Coaches
HHS Domains
Domain 7, Domain 8, Domain 10
Key Evidence Base
Fisher & Ury, Getting to Yes (1981); Miller & Rollnick, Motivational Interviewing (2013); Prochaska TTM
Module 5The History of Nutritional Science
6 hrsHow Dietary Guidance Went Wrong, and Why It Matters
Sections
1. The Ancel Keys Problem: Epidemiology as Advocacy
2. Industry Capture: The Sugar Research Foundation
3. The Dietary Guidelines: Policy Without Evidence
HHS Domains
Domain 1, Domain 9, Domain 10
Key Evidence Base
Kearns et al. (JAMA IM, 2016); Teicholz, The Big Fat Surprise (2014); 2026 HHS Dietary Guidelines overhaul
Module 6Food Systems, Public Health, and Physician Advocacy
6 hrsFrom the Patient's Plate to Agricultural Policy
Sections
1. The Gut Microbiome: The Forgotten Organ
2. Food Systems and the Social Determinants of Metabolic Health
3. Capstone: Building a Nutrition-Forward Clinical Practice
HHS Domains
Domain 6, Domain 9, Domain 10
Key Evidence Base
Sonnenburg & Bäckhed (Nature, 2016); USDA food environment data; WHO NCD prevention framework
MetFix Medical Nutrition - Faculty Guide · Page 2 of 3 · metfix.manus.space
MetFix Medical Nutrition - Faculty Guide · HHS Competency Map & Adoption · Page 3 of 3
HHS Competency Domain Coverage
| Domain | Label | Coverage in This Course | Modules |
|---|
| Domain 1 | Foundational Knowledge | Biochemistry of macronutrients, mitochondrial function, ROS signaling | Mod. 0, 1, 5 |
| Domain 2 | Macronutrient Metabolism | Carbohydrate, fat, and protein metabolism; clinical biochemistry | Mod. 1 |
| Domain 3 | Disease Mechanisms | Insulin resistance, T2DM pathophysiology, NAFLD, CVD | Mod. 1, 3 |
| Domain 4 | Micronutrients & Supplementation | Electrolytes, fat-soluble vitamins, clinical deficiency recognition | Mod. 1 |
| Domain 5 | Clinical Assessment | Metabolic screening, predictive diagnostics, HOMA-IR, TG:HDL | Mod. 0, 2 |
| Domain 6 | Diagnostic Interpretation | Optimal vs. standard lab ranges, physical exam findings | Mod. 0, 2, 6 |
| Domain 7 | Clinical Intervention | Disease-specific dietary protocols, medication deprescription | Mod. 2, 3, 4 |
| Domain 8 | Behavior Change | Psychology of dietary resistance, motivational interviewing, PON framework | Mod. 3, 4 |
| Domain 9 | Evidence-Based Practice | Critical appraisal of nutrition research, dietary guideline history | Mod. 5, 6 |
| Domain 10 | Advocacy & Systems Thinking | Food policy, social determinants, team-based care, physician advocacy | Mod. 4, 5, 6 |
CME Credit Details
Total Credit Hours
40 AMA PRA Category 1 Credits™ (pending accreditation)
Assessment Method
Per-module knowledge checks (5 questions each) + 50-question post-test
Passing Threshold
≥70% on post-test; unlimited attempts
Certificate
Auto-generated PDF certificate of completion with physician name, institution, and date
Accreditation Path
ACCME joint sponsorship with an accredited CME provider; or direct ACCME accreditation for sponsoring institution
Expiry
CME credits valid for 3 years from date of completion per standard ACCME policy
Curriculum Adoption Pathway
1
Curriculum Review
Department chair and curriculum committee review course content, learning objectives, and HHS competency mapping. Full content accessible at metfix.manus.space.
2
CME Accreditation
Submit course materials to your institution's CME office or an ACCME-accredited provider for joint sponsorship review. The course is structured to satisfy the 40-hour HHS requirement.
3
Integration Planning
Determine delivery model: standalone elective, integrated preclinical block, or residency didactic series. The modular structure supports all three formats.
4
Faculty Orientation
Designate a course director. MetFix provides a faculty orientation guide, slide decks for each module, and a case library for small-group discussion.
5
Student Enrollment
Students access the course at metfix.manus.space. Progress, quiz scores, and section completion are tracked automatically. Certificates of completion are generated on post-test passage.
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